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Glaucoma and Diabetes

University of California, San Francisco, UCSF Medical Center
Glaucoma and Diabetes
People with diabetes are at risk for several types of glaucoma. This article provides helpful information on prevention strategies and treatment options.

Primary Open-Angle Glaucoma

Type 2 diabetes is a risk factor for primary open-angle glaucoma. This has been demonstrated by large epidemiologic studies including the Los Angeles Latino Eye Study and the Blue Mountains eye study in Australia.

If you have type 2 diabetes, you should have been referred to an ophthalmologist at the time of diagnosis to look for signs of diabetic retinopathy, a disease in which high blood sugar damages the retina’s blood vessels. A diabetic patient should also have a yearly dilated exam so that any signs of glaucoma can also be identified.

In diabetic patients who have primary open-angle glaucoma, the glaucoma is treated the same way as for non-diabetic patients with open-angle glaucoma by lowering the eye pressure with medications, laser, and surgery if needed.

Neovascular Glaucoma

Neovascular glaucoma is another type of glaucoma for which diabetic patients are at higher risk. In this type of glaucoma, patients usually have a severe form of diabetic retinopathy, in which new vessels exhibit abnormal growth. These new vessels grow on the iris and over the drainage angle, causing scar formation and a form of angle-closure glaucoma.

The treatment plan includes treating the diabetic retinopathy, typically by a laser applied to the retina and injections of medications. Both treatments are intended to stop these abnormal new vessels from growing.  However, even if these vessels “regress,” the drainage angle may be so compromised that the eye pressure is uncontrolled even with eye drops. Unfortunately laser treatments such as SLT cannot be performed in these closed angles, so patients will sometimes require surgery to manage the neovascular glaucoma. Most ophthalmologists will choose to implant a glaucoma drainage device for immediate eye pressure control.

Steroid-Induced Glaucoma

The third type of glaucoma often associated with diabetes is steroid-induced glaucoma. This is a secondary open-angle glaucoma that is caused by steroid eye drops or injections.

Patients with diabetes can develop “diabetic macular edema,” which is when blood sugars damage the vessels in the retina, causing them to leak fluid. Fluid collects in the retina, which can cause vision loss. Treatments include laser applied to the retina, injections of medications intended to stop abnormal growth of blood vessels, and injections of steroids. This last category can cause steroid-induced glaucoma requiring eye drops, laser to the drainage system, or surgery such as a glaucoma drainage device to lower the eye pressure. Your ophthalmologist will discuss with you your various options, but sometimes it is difficult to balance a treatment that can improve your macular edema and vision (steroids) with the unwanted side effects (high eye pressure).

Prevention is Key

Just as it is important to control your blood sugars, blood pressure, and cholesterol for your overall health, it is important to control these factors for the health of your eyes. In addition to checking your blood sugars with a home monitoring device using a fingerstick, your primary care doctor will also have your blood drawn to check your hemoglobin A1c. This number is important because it gives a sense of how good your blood sugar control has been for the last 2-3 months. The lower the number, the better your diabetes control. Your ophthalmologist may ask you about your blood sugar control, and this is a useful number to report. If you have diabetes, talk to your doctors about strategies to improve blood sugar control, and continue your checkups even when you feel well and are seeing well. Caught early, the complications associated with diabetes can be more easily addressed.


This content was first posted on: October 11, 2017

The information provided here is a public service of the BrightFocus Foundation and should not in any way substitute for personalized advice of a qualified healthcare professional; it is not intended to constitute medical advice. Please consult your physician for personalized medical advice. BrightFocus Foundation does not endorse any medical product, therapy, or resources mentioned or listed in this article. All medications and supplements should only be taken under medical supervision. Also, although we make every effort to keep the medical information on our website updated, we cannot guarantee that the posted information reflects the most up-to-date research.

These articles do not imply an endorsement of BrightFocus by the author or their institution, nor do they imply an endorsement of the institution or author by BrightFocus.

Some of the content may be adapted from other sources, which will be clearly identified within the article.

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