Isabelle
Aubert

Dr. Isabelle Aubert works as a Senior Scientist at Sunnybrook Research Institute in Toronto, where she leads the Brain Repair Group. Her team, with key collaborators, is developing innovative therapies to halt neurodegeneration and promote brain repair, particularly for Alzheimer’s disease. Dr. Aubert uses MRI-guided focused ultrasound combined with microbubbles to modulate the blood-brain barrier. Her breakthrough discoveries on the neurobiological impact of blood-brain barrier modulation by ultrasound include the reduction of pathology and the stimulation of glial and neuronal regeneration in preclinical models of Alzheimer’s disease. Furthermore, she pioneered studies using ultrasound to deliver genes, cells and drugs to the brain, significantly enhancing treatment efficacy. Dr. Aubert teaches as a professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto, and serves as an advocate and Co-Vice Chair of wellness, inclusion, diversity, and equity. She enjoys learning from and mentoring the next generation of scientists. The recognition of Dr. Aubert’s international research accomplishments, commitment to advancing academic health sciences and public health outcomes, and service to the community reflects her position as Tier 1 Canada Research Chair in Brain Repair and Regeneration, and as an elected Fellow of the Canadian Academy of Health Sciences.