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Grants > Characterizing Brain Angiotensin System Updated On: Feb. 2, 2025
Alzheimer's Disease Research Grant

Characterizing Brain Angiotensin System

a headshot of Dr. Abadir

Principal Investigator

Peter Abadir, MD

Johns Hopkins Bayview Medical Center

Baltimore, MD, USA

About the Research Project

Program

Alzheimer's Disease Research

Award Type

Standard

Award Amount

$367,582

Active Dates

July 01, 2019 - June 30, 2023

Grant ID

A2019634S

Summary

This study is designed to evaluate specific factors that may play a role in development and progression of Alzheimer’s Dementia. Angiotensin receptors 1, 2 and 4 (AT1R, AT2R and AT4R) are found on brain cells and play an important function in brain vital functions. This study will examine changes in these receptors in brain cells in patients with Alzheimer’s dementia. We will also study the impact of a class of drugs that target these receptors and commonly used to treat high blood pressure.