Alzheimer's Disease Research News

In this issue: Researchers Discover Mechanisms Underlying Drusen Formation, President's Corner, Targeting Drusen Production in the Retina, FDA Approves New Treatment for Macular Degeneration, and more!

BrightFocus-funded researchers have shown how rare form of a gene variant may help protect against Alzheimer’s disease through changes in brain metabolism.

BrightFocus grantee Matthew Campbell discovers a way to manipulate the permeability of the blood-brain barrier to treat neurological disorders, including Alzheimer’s, and let drugs enter the brain.

Related BrightFocus research by an international team of scientists has identified a biological pathway and molecular sensor that induce inflammation in age-related macular degeneration (AMD) and lupus. The findings lend support for new treatment approaches.

The apolipoprotein E (APOE) gene impacts numerous human organs, including the brain, where three prevalent mutations confer differing risk for Alzheimer’s. However, their effects vary by race and genetic ancestry.

BrightFocus Foundation joins our Alzheimer’s research colleagues around the world in paying tribute to neurodegenerative disease expert John Q. Trojanowski, MD, PhD.