Zongchao Han, MD, PhD

Dr. Zongchao Han is Associate Professor of Ophthalmology at the University of North Carolina at Chapel Hill. He is an expert in the field of drug/gene deliveries, which utilizes nanoparticles and biomaterials for the treatment and study of ocular disorders. Dr. Han’s laboratory is developing novel therapies and tools for targeted ocular therapy, including age-related macular degeneration, retinitis pigmentosa, diabetic retinopathy, and retinoblastoma. His laboratory has developed a water-soluble antioxidant nanoceria formulation (PCT/US2018/018298). Their studies have shown promising selective antioxidant activity, anti-inflammatory response, and anti-angiogenesis both in in vitro and in vivo AMD models, indicating the feasibility of using this system as an alternative and novel approach for AMD patients for whom current therapies will not work or are not available.  In addition, Dr. Han is working on several biocompatible and biodegradable injectable hydrogels for the delivery of several types of therapeutic agents with sustained and controlled release, and innovative nano-delivery systems that have the capability to carry multiple imaging, targeting, and therapeutic moieties to restore vision. He has served as reviewer for more than 8 Institutes/Foundations, including National Academies of Sciences, Engineering, and Medicine (NASEM), Fight for Sight, German Research Foundation, French National Research Agency, University City Science Center QED program, and NEI Special Emphasis Panels.  His lab is currently supported by the BrightFocus Foundation, Thome Memorial Foundation, Carolina Center of Cancer Nanotechnology Excellence, and National Eye Institute.