Seth S Margolis, PhD

Dr. Margolis received his Bachelor of Science in Biochemistry at the University of Rochester in Rochester, NY. He completed his doctoral studies in the laboratory of Dr. Sally Kornbluth at Duke University Medical Center in Durham, North Carolina in the department of Pharmacology and Cancer Biology. In 2006, Margolis joined the laboratory of Dr. Michael Greenberg in the department of Neurobiology at Harvard University in Boston, Massachusetts as a postdoctoral fellow. During his postdoctoral tenure he focused his efforts on the molecular pathways that regulate excitatory synapse formation and investigated their relevance to the pathophysiology of cognitive disorders. In September of 2011, Margolis joined the Johns Hopkins University School of Medicine in Baltimore, Maryland as an Assistant Professor in the Department of Biological Chemistry. Currently, Margolis' research group is investigating the role of key negative regulators of synapse formation, which contribute to the pathophysiology of synapse loss in the Alzheimer's disease brain.