Relationship Between Fundus Autofluorescence And Cell Survival
1. Study vision cell structure with high-resolution images in living eyes.
2. Develop new technology to image individual cells that lie beneath the vision cells using their imaging properties.
3. Correlate vision cell structure and survival with genes associated with increased risk of advanced AMD.
Duncan JL, Ratnam K, Birch DG, Sundquist SM, Lucero AS, Zhang Y, Meltzer M, Smaoui N, Roorda A. Abnormal Cone Structure in Foveal Schisis Cavities in X-Linked Retinoschisis from Mutations in Exon 6 of the RS1 Gene. Invest Ophthalmol Vis Sci. 2011; 52(13):9614-23.
Talcott KE, Ratnam K, Sundquist SM, Lucero AS, Lujan BJ, Tao W, Porco TC, Roorda A, Duncan JL. Longitudinal study of cone photoreceptors during retinal degeneration and in response to ciliary neurotrophic factor treatment. Cone structure in retinal degeneration associated with mutations in the peripherin/RDS gene.
Duncan JL, Talcott KE, Ratnam K, Sundquist SM, Lucero AS, Day S, Zhang Y, Roorda A. Cone structure in retinal degeneration associated with mutations in the peripherin/RDS gene. Invest Ophthalmol Vis Sci. 2011 Mar 1;52(3):1557-66. Print 2011 Mar.
First published on: April 15, 2009
Last modified on: April 7, 2011