Ismael Santa-Maria Perez, PhD

Dr. Ismael Santa-Maria Perez is currently working as a Postdoctoral Research Scientist at Columbia University Medical Center in New York. During his studies, he worked as an undergraduate student at Tsukuba Research Institute in Tokyo and at Memorial Sloan Kettering Cancer Center in New York. He completed his doctoral training at the Autonomous University of Madrid where he studied the phosphorylation and aggregation of tau proteins, which are implicated in the pathogenesis of Alzheimer’s disease. Later, he performed post-doctoral work there for one year. He then obtained a fellowship from Neurological Diseases Research Centre Foundation and Queen Sofia Foundation’s Alzheimer’s Disease Project to study at Mount Sinai School of Medicine. His work covered both the role of grape-derived polyphenols in the attenuation of tau neuropathology in a mouse model of Alzheimer's disease and the implication of aggresome formation in the spreading of tau pathology. His current research at Columbia University in New York is studying the role of microRNAs on tau gene expression regulation in tangle-predominant Alzheimer’s disease.