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Grants > Treating Memory Loss in Alzheimer's Disease by Strengthening Synapses Updated On: Jun 17, 2025
Alzheimer's Disease Research Grant

Treating Memory Loss in Alzheimer's Disease by Strengthening Synapses

Translational Research & Clinical Interventions
a headshot of Dr. Dean

Principal Investigator

Camin Dean, PhD

University Medicine Goettingen

Berlin, Germany

About the Research Project

Program

Alzheimer's Disease Research

Award Type

Standard

Award Amount

$300,000

Active Dates

July 01, 2019 - March 31, 2023

Grant ID

A2019586S

Goals

People with Alzheimer’s disease lose the ability to remember things, especially things they recently learned. We recently discovered that mice missing a specific molecule called Synaptotagmin3, have better memory than normal mice. We now want to test if removing this molecule from mice with Alzheimer’s disease will improve their memory. If this works, it could be a way to treat humans with Alzheimer’s disease to improve their memory.

Summary

People with Alzheimer’s disease lose the ability to remember things, especially things they recently learned. We recently discovered that mice missing a specific molecule called Synaptotagmin3, have better memory than normal mice. We now want to test if removing this molecule from mice with Alzheimer’s disease will improve their memory. If this works, it could be a way to treat humans with Alzheimer’s disease to improve their memory.