Attributions

Blood And CSF Biomarkers Of Alzheimer's Disease

Gerry Shaw, PhD University of Florida

Summary

Alzheimer's disease is difficult to diagnose and it is also difficult to monitor the progression of the disease. We have developed two assays which can be used to monitor neurodegeneration using blood and cerebrospinal fluid (CSF) samples. The aim of the present proposal is to see if these assays can be used to monitor Alzheimer's disease.

Project Details

Alzheimer's disease is difficult to diagnose and it is also difficult to monitor the progression of the disease. Monitoring disease progression in a convenient fashion would allow the effectiveness of Alzheimer's disease therapies to be assessed in individual patients, which might be very beneficial. We have developed two assays which can be used to monitor neurodegeneration using blood and cerebrospinal fluid (CSF) samples. The aim of this project is to see if these assays, and modified assays based on them, can be used to specifically monitor the presence and progression of Alzheimer's disease.