Alzheimer's Disease, Before Plaques and Tangles

About the Research Project
Program
Award Type
Standard
Award Amount
$250,000
Active Dates
July 01, 2015 - June 30, 2018
Grant ID
A2015332S
Acknowledgement
Co-Principal Investigator(s)
Lee Martin, PhD, Johns Hopkins University
Summary
In this application, we propose to study the postmortem brain of individuals between 30 and 50 years of age and to identify those brains with the very early pathologic changes or lesions of Alzheimer’s disease. Then, we will study whether these lesions are associated with other abnormalities and whether they cause degeneration and death of brain nerve cells. Information obtained from this study could eventually help the development of new diagnostic tests and treatments for Alzheimer’s disease.
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