Expert

Is There a Connection Between Diet and Glaucoma?

University of California, San Francisco, UCSF Medical Center
Fruits and vegetables
Many people often wonder whether there are any diet or lifestyle changes they can make in order to take better care of themselves and their glaucoma. This article explores the current research concerning caffeine, alcohol, antioxidants, supplements, and more.

It is important to note that, at this juncture, the only proven method to treat glaucoma is to lower eye pressure. Also, when considering the population-based studies mentioned below that have examined the question of diet and glaucoma, they are primarily addressing whether dietary factors play a role in the development and diagnosis of glaucoma, and not whether they can help slow the progression of the disease.

Caffeine and Alcohol

An often asked question is whether caffeine affects eye pressure and glaucoma. It is known that caffeine can cause a several point rise in eye pressure that lasts for at least 90 minutes. However, whether that increase is of concern is best addressed between the patient and their eye doctor. A good rule of thumb is to exercise moderation with caffeine consumption. One cup of coffee is unlikely to cause any harm, but if you like to drink large amounts of coffee consider switching some of that consumption to decaffeinated. With regard to alcohol consumption, it is known that alcohol can lower eye pressure in the very short term, but there is no data to suggest that drinking alcohol reduces the risk of developing glaucoma or prevents its progression. As with almost everything, moderation is a good idea.

Antioxidants

As oxidative stress is thought to be an important feature of glaucoma, there have been several studies examining the relationship between antioxidant intake and glaucoma. In one prospective study,* no relationship was found between antioxidant intake, such as carotenoids, vitamin C, vitamin E, and the risk of developing glaucoma. However, there are other large studies that have shown a possible relationship between the consumption of foods rich in antioxidants, such as green leafy vegetables like kale and collards, and decreased glaucoma risk. In African-American women, there was a decreased risk of glaucoma with higher intake of certain fruits and vegetables high in vitamin A, vitamin C, and carotenoids. It has certainly been shown that increased consumption of fruits and vegetables and a heart-healthy diet will help decrease risk of heart disease and diabetes, and this is what I often recommend to my patients who ask about diet and glaucoma. More research needs to be done, however, to determine specific recommendations about antioxidants and glaucoma progression.

Dietary Nitrates (Green Leafy Vegetables)

Intake of dietary nitrates, derived mainly from green leafy vegetables, was associated with a 20 to 30 percent lower risk of primary open-angle glaucoma in two large studies examining the relationship between nutrition among other factors and various chronic diseases in men and women (the Nurses’ Health Study and the Health Professionals Follow-up Study). Interestingly, in patients with early visual field loss that was close to the central vision, the association was even stronger (40 to 50 percent lower risk). Again, it is important to note that this association was examining the risk of glaucoma diagnosis, not progression or worsening of existing glaucoma. Nevertheless, the advice to eat green leafy vegetables is probably a good one!

Omega Fatty Acids

A recently published prospective study found that a diet with a high omega 3:6 ratio intake, and thus low in omega 6, was associated with a higher risk of glaucoma. However, more studies are needed in order to determine whether recommending a diet with a lower omega 3:6 ratio is justified, especially since both omega-3 fatty acids and omega-6 fatty acids are important for heart health and other diseases. Omega-3 fatty acids are typically found in vegetable oils, green vegetables such as kale, and fatty fish such as salmon. Omega-6 fatty acids are found in many types of vegetable oils and can help lower LDL cholesterol. Thus, at this juncture, it would not be recommended to  modify your omega-3 and omega-6 consumption since both have been shown to be associated with many health benefits.

Supplements

Another common question is whether there are any supplements that can be taken to reduce the risk of glaucoma or to treat glaucoma. Currently, there is no convincing data that supplementation can help in preventing or treating glaucoma. Due to the fact that supplements are made by many different suppliers and there is no legal or regulatory standardization in the United States, and that they can be expensive, I usually advise patients not to take additional “eye” supplements other than a standard multivitamin, which was demonstrated by a randomized controlled trial.

Please note that there is a specific supplement intervention, however, that could delay and possibly prevent intermediate age-related macular degeneration from progressing to the advanced stage. It is very important to ask your ophthalmologist if this supplement would be beneficial to you if you have macular degeneration.

Summary

Clearly, there is still much to be learned about the relationship between diet and glaucoma. For now, it is probably wisest to eat a healthy, well-balanced diet and to talk to your eye doctor about what recommendations he or she has for your specific situation.

*Prospective study: A research study that follows groups of individuals over time who are alike in many ways but differ by a certain characteristic (for example, people who eat fruits and vegetables and those who do not) and compares them for a particular outcome (such as progression of glaucoma).

Resources:

This content was first posted on: March 17, 2017

The information provided here is a public service of the BrightFocus Foundation and should not in any way substitute for personalized advice of a qualified healthcare professional; it is not intended to constitute medical advice. Please consult your physician for personalized medical advice. BrightFocus Foundation does not endorse any medical product, therapy, or resources mentioned or listed in this article. All medications and supplements should only be taken under medical supervision. Also, although we make every effort to keep the medical information on our website updated, we cannot guarantee that the posted information reflects the most up-to-date research.

These articles do not imply an endorsement of BrightFocus by the author or their institution, nor do they imply an endorsement of the institution or author by BrightFocus.

Some of the content may be adapted from other sources, which will be clearly identified within the article.

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