Gabriela Chiosis, PhD
The Chiosis lab uses a chemical biology approach to understand, diagnose, and treat cellular processes associated with chronic molecular stress, with the ultimate-goal of developing therapeutics and diagnostics for use in the treatment of human disease. The lab has authored >165 scientific articles on biomedical subjects from probe and drug discovery to mechanistic and translational investigations. It holds >500 patents and patent applications on to the discovery of therapeutic agents and diagnostics in human medicine, and also related to methods of treatment. These innovations provide a platform for precision medicine for diagnosis and treatment of disease that is based on the aberrant properties of protein-protein interaction networks. Compounds and diagnostics discovered by the lab are currently in clinical evaluation in cancer and Alzheimer’s disease.