Florian Sennlaub, MD, PhD

Dr. Florian Sennlaub received his medical degree in Germany, his doctoral training and PhD in Paris, and his postdoctoral training in Montréal. He holds a tenure-track director of research position at the French National Health Institute and is head of the Department of Pathophysiology and Therapeutics at the Vision Institute in Paris, France. His laboratory focuses on the pathogenic role of the chronic accumulation of immune cells, in particular macrophages, in age-related macular degeneration (AMD). His recent work has demonstrated how the genetic AMD-risk variants affect macrophage function, impairing subretinal immune suppression, and inflammation resolution. Together his findings emphasize the role of the AMD-risk variants in inflammation in AMD and open new therapeutic avenues to inhibit pathogenic, non-resolving, subretinal macrophage accumulation in AMD. Dr. Sennlaub is the recipient of the Prix de la Fondation de l’oeil (France) and has authored and co-authored 95 articles.