David Irwin, MD

Dr. David Irwin is an assistant professor of neurology at the University of Pennsylvania Perelman School of Medicine. Dr. Irwin is a former post-doctoral fellow at the Penn Center for Neurodegenerative Disease Research and Frontotemporal Degeneration Center. Dr. Irwin’s research is focused on clinical biomarker discovery through comparative clinicopathological studies in neurodegenerative disease using novel digital image analysis methods for use on human autopsy histology samples. The overarching goal of this approach is to improve the ante mortem diagnosis of underlying neuropathology for improved clinical trials targeting specific pathogenic proteins (eg, tau, TDP-43 [transactive response DNA binding protein 43], alpha-synuclein) that characterize these disorders.