Attributions

A Novel Treatment Strategy for Neurorepair in Alzheimer's Disease

Bruce Cohen, MD, PhD McLean Hospital

Co-Principal Investigators

Kai Sonntag, MD, PhD McLean Hospital

Summary

In this project, 'adult' stem cells will be used as a delivery system to deliver sAPP to brain regions undergoing neurodegeneration. The hypothesis is that sAPP will work together with growth factors to protect and repair cholinergic neurons in the brain, thereby representing a potential for therapeutic treatment in humans with AD.