Expert

Diet and Alzheimer’s Disease

Swank Memory Care Center, Christiana Care Health System
Health foods, including whole grains, green leafy and other vegetables, berries, fish, poultry, beans, nuts, and olive oil
Learn helpful information on the role of diet and brain health, based on the latest research.

Food serves so many important purposes in our lives. Food-related activities bring us together with the people who are important in our lives. Food gives us pleasure, stimulation, and comfort. The behavioral disorders related to food create or sustain terrible distress. Food deficiency or deprivation is a source of great suffering. In so many ways, food can make life better or worse. It can make health better or worse, too.

Much research has been directed at understanding how dietary patterns affect the risk for Alzheimer’s disease and other dementias, and here too food can play a positive, health-improving role…or a destructive and disease-promoting role. The World Health Organization recently concluded that many cases of cognitive decline could be delayed or prevented through adopting a healthier lifestyle.1 Physical activity, diet, smoking cessation, and attention to chronic medical diseases are all important contributors to healthier cognitive aging. So, what do we know about food and Alzheimer’s disease? 2,3

Foods that May Increase the Risk of Alzheimer’s

First, we know that an unhealthy diet can promote cognitive decline along with other health problems. Scientists have looked at what they call the “Western diet,” a pattern rich in convenient, processed foods and rich in animal products. The typical western diet is high in total fat, saturated fat, cholesterol, sodium, and processed grains, large amounts of added sugar. This eating pattern has been linked to obesity, diabetes, and heart disease. A high intake of saturated and trans fats increase the body’s levels of oxidative stress and inflammatory response, harmful processes which contribute to the development of dementia. The take-away message? Cut down on total caloric intake, saturated and trans fats, and sugar.

Foods that May Decrease the Risk of Alzheimer’s

Next, we know that a healthier diet can protect cognitive functioning while also improving other aspects of health. Most of the research on diet and Alzheimer’s has focused on the Mediterranean diet (MD), an eating pattern that emphasizes healthy fats such as olive oil, fresh fruits and vegetables, legumes, nuts, and less dairy food, red meat, butter or margarine, sweetened beverages, and pastries. Moderate wine consumption is included in some, but not all, European and Middle Eastern populations who have adopted the MD.

The DASH Diet

In the United States, concern about lifestyle and rampant high blood pressure led our National Heart, Lung, and Blood Institute to propose a set of dietary recommendations known as the Dietary Approaches to Stop Hypertension (DASH) Diet. The DASH Diet emphasizes many MD components as well as a reduction in overall consumption of carbohydrates and sodium. It has been shown to reduce blood pressure.

The MIND Diet

More recently, the Mediterranean-DASH Intervention for Neurodegenerative Delay Diet, known popularly as the MIND Diet, has been shown to slow down cognitive decline. The MIND Diet takes elements of MD and DASH and recommends dietary focus on the “good” foods such as whole grains, green leafy and other vegetables, berries, fish, poultry, beans, nuts, and olive oil while minimizing intake of “bad” foods such as red meats, butter, margarine, cheese, fast foods, and sweets. One study found that adherents to the MIND Diet demonstrated more successful cognitive aging and the MIND Diet provided even better protection against Alzheimer’s disease in this study than the DASH or MD diets.4

Can Vitamins and Supplements Decrease the Risk of Alzheimer’s?

Not all that we eat falls into the category of food, and many vitamins or supplements have also been studied in relationship to Alzheimer’s disease risk. We certainly need enough of the essential vitamins such as folic acid, B12, E, and D. Excessive E or D, however, accumulate in our fat tissues and are not beneficial. Curcumin, omega 3 fatty acids, and cocoa are among the dietary additives still being researched for a deeper understanding of their risks and benefits. A study recently published in the Journal of the American Medical Association cautioned us that many dietary supplements marketed for the prevention or treatment of cognitive decline are not well supported by credible evidence.5

Summary

Our growing appreciation of the relationship between diet and brain health, and the behaviors we choose to change or continue, will shape the health of our aging population. Along with other lifestyle choices, our food consumption habits can have constructive or destructive effects on brain health. We are armed with the knowledge that can benefit society and delay or prevent many cases of cognitive decline.

Food and Brain Health
Healthy FoodsFoods to Avoid
  • Whole grains
  • Fresh fruits
  • Vegetables
  • Fish
  • Beans
  • Nuts
  • Olive oil
  • Red meats
  • Butter
  • Margarine
  • Cheese
  • Fast foods
  • Sweets
  • High-sodium foods

Resources:

References and Further Reading:

  1. Risk reduction of cognitive decline and dementia: WHO guidelines. Geneva: World Health Organization; 2019. License: CC BY-NC-SA 3.0 IGO.
  2. Samadi M, Moradi S, Moradinazar et al. Dietary pattern in relation to the risk of Alzheimer’s disease: a systematic review. Neurological Sciences 2019.
  3. Yusufov M, Weyandt LL, Piryatinsky I. Alzheimer’s disease and diet: a systematic review. Int J of Neuroscience 2017;127(2):161-75.
  4. Morris et al. MIND diet associated with reduced incidence of Alzheimer’s disease. Alzheimer’s & Dementia 2015;11:1015-1022
  5. Hellmuth J, Rabinovici GD, Miller BL. The rise of pseudomedicine for dementia and brain health.
This content was first posted on: September 9, 2019

The information provided here is a public service of the BrightFocus Foundation and should not in any way substitute for personalized advice of a qualified healthcare professional; it is not intended to constitute medical advice. Please consult your physician for personalized medical advice. BrightFocus Foundation does not endorse any medical product, therapy, or resources mentioned or listed in this article. All medications and supplements should only be taken under medical supervision. Also, although we make every effort to keep the medical information on our website updated, we cannot guarantee that the posted information reflects the most up-to-date research.

These articles do not imply an endorsement of BrightFocus by the author or their institution, nor do they imply an endorsement of the institution or author by BrightFocus.

Some of the content may be adapted from other sources, which will be clearly identified within the article.

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