What We Do

BrightFocus Foundation funds exceptional scientific research worldwide to defeat Alzheimer’s disease, macular degeneration, and glaucoma and provides expert information to empower individuals and families.

Scientist conducting cell culture experiment in the lab.
Alzheimer’s Disease Research grant recipient, Daheun Chung, PhD
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Our Work

Scientist using a microscope in a lab.

Fund Innovative Science

Our Robust Research Program

We provide initial funding for highly innovative, experimental ideas with the most significant promise to change a disease’s trajectory. Most of our grants support early-stage research, ensuring fresh perspectives and novel discoveries that fuel the field, delivering an increased return on research investment over time. BrightFocus grants undergo rigorous evaluation by the world’s top scientists and clinicians who serve on our scientific review committees.

A speaker discusses the latest findings in Alzheimer's disease research.

Invest in Scientists

Paving the Future of the Field

BrightFocus educates, trains, and supports the next generation of brain and vision scientists. Taught by experts in the field, our signature Fast Track workshops and global travel fellowships have accelerated the careers and transformative ideas of thousands of early-career scientists worldwide.

A couple hugging.

Inform the Public

Sharing Public Resources and Educating Communities

BrightFocus empowers individuals and families with trusted information on research findings, healthy living, risk reduction, treatments, and living with diseases of mind and sight. We offer expert-vetted resources, community events, virtual programming, partnerships, and entertainment connecting the public to researchers, doctors, and expert information in multilingual formats.

Our Commitment to Health Equity

Every population is impacted by Alzheimer’s, macular degeneration, and glaucoma, but they are not impacted equally. Health equity starts in the lab, and disparities are a public health problem that must be solved to prevent, treat, and cure mind and sight diseases. Central to the vision and mission of BrightFocus Foundation is a drive to fund the most promising scientific research so that we can all live a longer and more rewarding life.

BrightFocus is committed to:

  • Funding the most promising and innovative research that approaches the diseases from diverse angles to have the best chance of defeating them for good.
  • Growing community to reflect better and support every person impacted by mind and sight diseases.
  • Supporting and educating scientists from all backgrounds to foster creativity and innovation in addressing complex scientific challenges. We strongly encourage applications from individuals who are from groups underrepresented in the field to apply for our grants. Nearly 45% of our funded researchers across 25 countries are women and from a non-white racial background.
  • Reflecting the broad community we serve by hiring with a mindset of inclusivity. We believe diverse perspectives and representation amongst our staff and leadership are essential to better understanding and serving everyone.
  • Increasing awareness across every community about mind and sight diseases, with an emphasis on under-resourced communities where there is a significant distrust in healthcare professionals and a lack of understanding about the diseases and the importance of taking them more seriously.
  • Growing our strategic diversity, equity, and inclusion partnerships to better educate and engage with underserved communities in a meaningful way that provides value to these communities. We believe that change starts from within, and that success occurs when community ambassadors build relationships and trust as agents of change over time.
  • Listening to and making changes in our initiatives to reflect better the voices of the people we serve.
  • Ensuring our informational programs and materials meet the highest ADA standards for accessibility and low vision possible.
  • Increasing our free multilingual resources.
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Virtual Programs

Information Program Highlights

Our free information programs provide insight and support for affected individuals and their loved ones.

Zoom In on Dementia & Alzheimer’s

This live, interactive program featuring renowned research scientists and clinicians shares the latest research news and information, and participants can ask questions live or watch on demand. Topics range from newly approved treatments to genetics, risk reduction, and more.

Macular Chats and Glaucoma Chats

Our monthly, live audio discussions with vision experts empower people living with macular degeneration and glaucoma with the latest research and tips for living with low vision.

Age-Related Macular Degeneration Community Circle

This monthly, virtual program is designed to provide a place where people with macular degeneration can join together to share tips, ask questions, and build community.

Annual Report and Research Grant Portfolios

Every year, BrightFocus produces an annual report and research grant portfolios to highlight our currently funded research.

Powering Innovative Research

Read about the latest research advancements to diagnose, slow the progression, treat, and ultimately cure these diseases of mind and sight.
Stacey Sukoff Rizzo, PhD, far left, shares feedback with students.

Article

4 Takeaways from Alzheimer’s Fast Track 2025

This innovative meeting hosted by BrightFocus Foundation bridges cutting-edge science, mentorship, and community building for early-career researchers.

Understanding Alzheimer's and Exploring New Frontiers in Treatment thumbnail.

Article

Understanding Alzheimer’s & Exploring New Frontiers in Treatment

Watch a conversation inspired by the documentary film Taking Care and the latest research in Alzheimer’s therapies.

Article

Shaping the Future of National Alzheimer’s Research Priorities

BrightFocus Foundation’s VP of Scientific Affairs helped set national research priorities at the federal Alzheimer’s Disease-Related Dementias Summit, influencing how billions in NIH funding will advance dementia research and care.

A researcher looking through a microscope in a lab.

Press Release

2025 Research Portfolios Spotlight Breakthrough Science

BrightFocus is proudly supporting 186 cutting-edge research grants, fueling the global fight against Alzheimer’s disease, macular degeneration, and glaucoma.

An older man sits on a couch with a glass of water in one hand and a pill pinched between the thumb and forefinger of the other, bringing the pill close to his mouth

Article

New Supplement to Prevent Macular Degeneration Inspires Deeper Search for Cures

A Macular Degeneration Research-funded scientist launched a supplement based on a link he discovered between the eye disease and Parkinson’s disease. Now he’s continuing research in the hopes of finding novel cures.

Dr. Sharyn Rossi and Dr. Keith Hengen.

Article

New Clues in the Fight Against Alzheimer’s: Q&A with Dr. Keith Hengen

During World Alzheimer’s Month, Alzheimer’s Disease Research grantee Dr. Keith Hengen joined BrightFocus’ Dr. Sharyn Rossi on Instagram Live to talk brain health—how the brain functions, why quality sleep matters, and tips to keep your brain healthy.