Apply for a Research Grant

BrightFocus provides research funds for U.S. domestic as well as international researchers pursuing pioneering research leading to greater understanding, prevention, and treatment of Alzheimer’s disease, macular degeneration, and glaucoma.

Alzheimer’s Disease Research Request for Proposals

Macular Degeneration Research Request for Proposals

National Glaucoma Research Request for Proposals

To start a new application and upload attachments, you must use our ProposalCentral application portal to apply online. Note: Your organization must be registered with ProposalCentral to apply.

Scientist working in lab.
Macular Degeneration Research grant recipient, Yong-Su Kwon, PhD
A female researcher in the lab.

Our Funding Philosophy

It is our firm belief that having the courage to invest in innovative ideas will lead to revolutionary therapies. BrightFocus provides initial funding for highly innovative experimental ideas, including interdisciplinary investigations that may apply to two or three of the BrightFocus disease interests. Most of the awardees use the BrightFocus award funds to demonstrate key findings that lead to later interest and additional funding from industrial or governmental funding agencies.

Grant Application Resources

Frequently Asked Questions

Get answers to applicants’ frequently asked questions, from eligibility to the review process, categorized by each disease program.

Read FAQs

Guidelines

From file type and size to formatting requirements, ensure your application checks the necessary boxes.

Read Guidelines

Terms & Conditions

Your guide to understanding the conditions of funding and the definitions and abbreviations used throughout the grant agreement.

Read Terms & Conditions
A male researcher in the lab.
National Glaucoma Research-funded scientist Ignacio Provencio, PhD.

News

Recent News & Breakthroughs

Browse research news and breakthroughs from BrightFocus-funded scientists.
Portrait of mother wearing glasses and son.

How Early Research Funding Is Transforming Glaucoma Detection

If you’ve been diagnosed with glaucoma in the past 15 years, you have likely unknowingly witnessed what early research funding can do for the 4 million Americans living with this sight-stealing disease.

Ophthalmologist examining optical coherence tomography (oct) scan results on a computer, utilizing light waves for non-invasive cross-section imaging of the retina.

Early Research Funding Is Essential to Saving Sight From Macular Degeneration

Medicine’s biggest breakthroughs often start out as the smallest of ideas. BrightFocus Foundation’s Macular Degeneration Research supports bold, early-stage science across a wide range of approaches.

Glowing brain with polygonal mesh on colorful tech background.

Unlocking the Brain’s Regenerative Potential to Fight Alzheimer’s

María Llorens-Martín is investigating why the brain stops making new cells in Alzheimer’s—and how fixing that process could change lives.

Laboratory assistant draws blood from a patient's vein with a disposable syringe.

Breaking News Dispatch: New Findings on GLP-1 Drugs and Alzheimer’s, Novel Treatments in Development, and More

Get the latest news from the 2025 Clinical Trials on Alzheimer’s Disease (CTAD) conference.

Stacey Sukoff Rizzo, PhD, far left, shares feedback with students.

4 Takeaways from Alzheimer’s Fast Track 2025

This innovative meeting hosted by BrightFocus Foundation bridges cutting-edge science, mentorship, and community building for early-career researchers.

Understanding Alzheimer's and Exploring New Frontiers in Treatment thumbnail.

Understanding Alzheimer’s & Exploring New Frontiers in Treatment

Watch a conversation inspired by the documentary film Taking Care and the latest research in Alzheimer’s therapies.

Shaping the Future of National Alzheimer’s Research Priorities

BrightFocus Foundation’s VP of Scientific Affairs helped set national research priorities at the federal Alzheimer’s Disease-Related Dementias Summit, influencing how billions in NIH funding will advance dementia research and care.

A researcher looking through a microscope in a lab.

2025 Research Portfolios Spotlight Breakthrough Science

BrightFocus is proudly supporting 186 cutting-edge research grants, fueling the global fight against Alzheimer’s disease, macular degeneration, and glaucoma.

An older man sits on a couch with a glass of water in one hand and a pill pinched between the thumb and forefinger of the other, bringing the pill close to his mouth

New Supplement to Prevent Macular Degeneration Inspires Deeper Search for Cures

A Macular Degeneration Research-funded scientist launched a supplement based on a link he discovered between the eye disease and Parkinson’s disease. Now he’s continuing research in the hopes of finding novel cures.

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