Microstructural and Biomechanical Properties of Human Sclera

About the Research Project
Program
Award Type
Standard
Award Amount
$100,000
Active Dates
April 01, 2009 - March 31, 2011
Grant ID
G2009035
Acknowledgement
Goals
This research is aimed at identifying whether changes in peripapillary human scleral microstructure and mechanical properties occur within human donor eyes of varying ages, races, and in the presence or absence of glaucoma. Such information will be important in quantifying the biomechanical environment of the optic nerve head. These studies may also eventually lead to improved diagnostic tools for glaucoma.
Summary
In our research we:
- Use sophisticated experiments to characterize how the mechanical properties of the sclera vary with age, race, and glaucoma; and
- Use sophisticated imaging techniques to quantify how such changes occur.
Our team is especially excited about utilizing state of the art techniques in biomechanics and bioimaging to develop new and innovative diagnostic tools for glaucoma.
Related Grants
National Glaucoma Research
Why Certain Retina Ganglion Cells Stay Strong in Glaucoma
Active Dates
July 01, 2024 - June 30, 2026
Principal Investigator
Mengya Zhao, PhD
Current Organization
University of California, San Francisco
Why Certain Retina Ganglion Cells Stay Strong in Glaucoma
Active Dates
July 01, 2024 - June 30, 2026

Principal Investigator
Mengya Zhao, PhD
Current Organization
University of California, San Francisco
National Glaucoma Research
How the Microenvironment Affects Schlemm’s Canal Cell Behavior
Active Dates
July 01, 2024 - June 30, 2026
Principal Investigator
Samuel Herberg, PhD
Current Organization
SUNY Upstate Medical University
How the Microenvironment Affects Schlemm’s Canal Cell Behavior
Active Dates
July 01, 2024 - June 30, 2026

Principal Investigator
Samuel Herberg, PhD
Current Organization
SUNY Upstate Medical University
National Glaucoma Research
The Impact of Glaucoma on Light-Mediated Mood and Sleep Disorders
Active Dates
July 01, 2024 - June 30, 2026
Principal Investigator
Xiaorong Liu, PhD
Current Organization
University of Virginia
The Impact of Glaucoma on Light-Mediated Mood and Sleep Disorders
Active Dates
July 01, 2024 - June 30, 2026

Principal Investigator
Xiaorong Liu, PhD
Current Organization
University of Virginia