What Is Glaucoma?

Glaucoma is a group of eye diseases that damage the optic nerve, the bundle of nerve fibers that carries information from the eye to the brain. It can lead to vision loss and blindness. Although there is no cure, medications and surgery can help slow the disease’s progression. Learn about the signs and symptoms of glaucoma, treatments, prevention techniques, and ways to care for yourself or a loved one.

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Program Impact

Accelerating Research Toward a Cure

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National Glaucoma Research-funded scientist Hannah Youngblood, PhD.

National Glaucoma Research, a BrightFocus Foundation program, funds a wide range of innovative scientific approaches that explore the root causes of this eye disease.

With our funding, scientists around the world are developing, testing, and investigating hundreds of ideas to prevent, treat, and cure glaucoma.

We’ve invested nearly $51 million in glaucoma research to date across 496 research grants.

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Understanding Glaucoma

Types of Glaucoma

There are two main forms of glaucoma: open-angle and angle-closure. There are also several other less common forms of this eye disease, including normal-tension, childhood, and secondary glaucoma.

The most common types of glaucoma often have no symptoms until irreversible damage to the eye has already occurred and vision loss has begun. That’s why glaucoma is sometimes called the “sneak thief of sight,” and why regular screening and early detection are so important.

Learn about the different types of glaucoma:

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Open-Angle Glaucoma

The most common form, affecting approximately 70-90% of people with the disease, open-angle glaucoma is a chronic, slowly progressing condition that has few or no symptoms until peripheral vision loss has already begun. In the U.S., this type impacts African American and Hispanic populations at higher rates than other ethnicities.

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Angle-Closure Glaucoma

This second most common type of glaucoma is a largely inherited disorder caused by a narrow angle in the eye’s passageway where aqueous fluid would normally flow.

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Chronic Angle-Closure Glaucoma

This type of glaucoma progresses more slowly and can damage the optic nerve without symptoms, similar to open-angle glaucoma.

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Acute Angle-Closure Glaucoma

This occurs suddenly when the flow of aqueous humor between the iris and the lens of the eye is blocked. This rare medical emergency must be treated immediately or blindness could result in a day or two.

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Normal-Tension Glaucoma

This form is very similar to primary open-angle glaucoma, except that damage to the optic nerve occurs even though eye pressure is not elevated.

Secondary Glaucoma

Secondary glaucoma can be open-angle or closed-angle and is the result of some other medical condition in the eye or the body.

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How Glaucoma Affects Vision

How Open-Angle Glaucoma May Affect Vision

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Normal Vision

This is an example of normal vision, but it could also be seen as how someone sees during the beginning stages of open-angle glaucoma. Because there are no symptoms initially, regular eye examinations are very important.

Early Glaucoma

Early symptoms may include a gradual and often imperceptible failing of side (peripheral) vision.

Advanced Glaucoma

Only a small central area of vision remains during the advanced stages of glaucoma. Eventually, damage to the optic nerve will result in total blindness.

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A group of six children of diverse backgrounds smiling and standing close together with their arms around each other. They are outdoors on a sunny day with a tree and blue sky in the background, with a vignette effect around the edges.
A group of six children of diverse backgrounds smiling and standing close together with their arms around each other. They are outdoors on a sunny day with a tree and blue sky in the background, with a strong blur effect around the edges, focusing on the center child.
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Who is at Risk of Developing Glaucoma?

The most common types of glaucoma have completely different symptoms. However, there are some general risk factors to keep in mind, including:

 

  • High eye pressure
  • Family history of glaucoma
  • Being age 40 and older for African Americans
  • Being age 60 and older, particularly for Hispanics/Latinos

Browse other potential risk factors and how to lower your risk.

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By The Numbers

Facts & Figures

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4 Million+ Americans

More than four million Americans aged 40 and older are living with glaucoma, 2.7 million of whom are affected by its most common type, open-angle glaucoma.

Glaucoma is the second leading cause of blindness in the world, affecting 80 million people.

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Eye Pressure: A Major Risk Factor

Eye pressure is a major risk factor for glaucoma, but not every person with increased eye pressure will develop glaucoma. Glaucoma can even develop without increased eye pressure.

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Early Detection Can Protect Vision

Currently, there is no cure for glaucoma; however, early detection and treatment can slow the progression of the disease and protect remaining vision.

Resources

Explore Helpful Resources & Information

Browse expert-vetted articles, brochures, and other resources to help you take charge of your eye health.
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Glaucoma Chats

What I Wish I Knew About Glaucoma: Your Top Questions Answered

In this chat, Dr. Poonam Misra addresses some of the most common questions listeners have shared over the past year—from treatment options and lifestyle considerations to the latest educational resources.

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Glaucoma Chats

Dry Eye and Glaucoma

Dr. Astrid Werner explains what causes dry eye, how to recognize the symptoms, and effective treatment options—including preservative-free drops, artificial tears, and eyelid care routines.

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Story

Paying Forward the Benefits of Research

Meet Richard, a loyal donor to BrightFocus’ National Glaucoma Research and Macular Degeneration Research programs.

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Glaucoma Chats

Can We Restore Vision Loss from Glaucoma? What the Research Says

Join us for a fascinating conversation with Dr. Lucy Q. Shen as we explore cutting-edge research into restoring vision loss from glaucoma.

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Downloadable Resource

The Top Five Questions to Ask Your Eye Doctor

Preparing ahead of time can help you best manage your vision health. Here are some questions you can take along when you visit the eye doctor.

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Glaucoma Chats

Staying Ahead of Glaucoma: Why a Proactive Approach Matters

Learn how early intervention can preserve sight and improve quality of life.

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Expert Information

Diet, Exercise, and Other Habits That May Help Reduce Glaucoma Risk

A healthy lifestyle can benefit more than just your heart — it may help protect your vision, too. Learn what the latest research says about diet, exercise, sleep, and stress management in glaucoma care.

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Glaucoma Chats

Promising Research to Defeat Glaucoma

Learn about some of these groundbreaking research projects and how they are advancing earlier detection, risk reduction, treatments, and, ultimately, a cure for glaucoma.

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Expert Information

3 Subtle Signs Your Glaucoma May Be Getting Worse

In between doctor visits, you are the best advocate for detecting changes to your glaucoma. Discover the key symptoms to watch for and how early action can help protect your vision.

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