AparnaLakkaraju
PhD
Location
USA
Current Organization
University of California, San Francisco
Biography
Dr. Aparna Lakkaraju is a Professor of Ophthalmology at UCSF and an internationally recognized expert in retinal biology. Her research focuses on the retinal pigment epithelium (RPE) and its dysfunction in macular degenerations. Dr. Lakkaraju has led major NIH- and foundation-funded projects to uncover how mitochondrial stress, complement activation, and impaired autophagy contribute to RPE damage and vision loss. She has pioneered imaging methods that track mitochondrial function and intracellular trafficking in live retinal tissues. An esteemed mentor, she has trained over 50 vision scientists and directs the Postdoctoral Training Program in Ophthalmology and co-directs the Pharmaceutical Sciences and Pharmacogenomics graduate program at UCSF. Dr. Lakkaraju currently serves as Chair of the NIH National Eye Institute’s Board of Scientific Counselors. She is also the recipient of the 2021 Lorraine Maresca Innovative Research Award from BrightFocus Foundation.
Grants
Macular Degeneration Research
How Metabolic Stress Can Drive Macular Degeneration
Active Dates
July 01, 2025 - June 30, 2027
Principal Investigator
Valencia Fernandes, PhD
Current Organization
University of California, San Francisco
How Metabolic Stress Can Drive Macular Degeneration
Active Dates
July 01, 2025 - June 30, 2027
Principal Investigator
Valencia Fernandes, PhD
Current Organization
University of California, San Francisco
Macular Degeneration Research
How Does Mechanical Stress Injure the Retinal Pigment Epithelium in AMD?
Active Dates
July 01, 2021 - June 30, 2024
Principal Investigator
Aparna Lakkaraju, PhD
Current Organization
University of California, San Francisco
How Does Mechanical Stress Injure the Retinal Pigment Epithelium in AMD?
Active Dates
July 01, 2021 - June 30, 2024
Principal Investigator
Aparna Lakkaraju, PhD
Current Organization
University of California, San Francisco
Macular Degeneration Research
Uncovering the Developmental Mechanism of Chorioretinal Anastomoses
Active Dates
July 01, 2021 - December 31, 2024
Principal Investigator
Tyson Kim, MD, PhD
Current Organization
University of California, San Francisco
Uncovering the Developmental Mechanism of Chorioretinal Anastomoses
Active Dates
July 01, 2021 - December 31, 2024
Principal Investigator
Tyson Kim, MD, PhD
Current Organization
University of California, San Francisco
Macular Degeneration Research
Can RPE-Derived Exosomes Contribute to Subretinal Drusenoid Deposits?
Active Dates
July 01, 2015 - June 30, 2017
Principal Investigator
Aparna Lakkaraju, PhD
Current Organization
University of California, San Francisco
Can RPE-Derived Exosomes Contribute to Subretinal Drusenoid Deposits?
Active Dates
July 01, 2015 - June 30, 2017
Principal Investigator
Aparna Lakkaraju, PhD
Current Organization
University of California, San Francisco
Macular Degeneration Research
Apolipoprotein E and Cholesterol Lowering Drugs in Age-Related Macular Degeneration
Active Dates
April 01, 2009 - March 31, 2013
Principal Investigator
Aparna Lakkaraju, PhD
Current Organization
University of California, San Francisco
Apolipoprotein E and Cholesterol Lowering Drugs in Age-Related Macular Degeneration
Active Dates
April 01, 2009 - March 31, 2013
Principal Investigator
Aparna Lakkaraju, PhD
Current Organization
University of California, San Francisco
News Featuring This Grantee
Research News
Unlocking Secrets of Waste Disposal in the Eye
Explore research into the eye's intricate waste disposal system, crucial in preventing macular degeneration.
Research News
Targeting Drusen Production in the AMD Retina
Scientists discovered how a combination of genetic and environmental risk factors leads to the formation of small lipid droplets, which can be an early sign of macular degeneration.