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Alzheimer's Disease Research Macular Degeneration Research National Glaucoma Research

2013 BrightFocus Research Awards

Alzheimer's Disease


Macular Degeneration

Alzheimer's Disease

Tau Spread in Alzheimer's Disease
Hirohide Asai, M.D., Ph.D.
Boston University School of Medicine

A Molecules-to-Circuits Approach to Understanding the Causes of Memory Impairment in Alzheimer's Disease
Adam W. Bero, Ph.D.
Massachusetts Institute of Technology

Are Tau Oligomers the Elusive Toxic Species of Tau within Alzheimer's Disease?
Lester I. Binder, B.A., M.Phil., Ph.D.
Michigan State University

How Inflammation in the Brain and Periphery Affects Brain Pathology in Common Dementias such as Alzheimer's Disease
Paramita Chakrabarty, Ph.D.
University of Florida

Decay of Memory Networks in Alzheimer’s Disease
Jasmeer P. Chhatwal, M.D., Ph.D.
Massachusetts General Hospital, Harvard Medical School

Investigating Whether ADAM10 Protein Modulates Birth of New Neurons in Adult Brain
Se Hoon Choi, Ph.D.
Massachusetts General Hospital

A New Method to Identify Protein and Genes Involved in Alzheimer's Disease
Carlos Cruchaga, Ph.D.
Washington University

Searching the Main Actors Involved in Human Dementia
Dolores Del Prete, Ph.D.
Albert Einstein College of Medicine

Exploring New Ways to Prevent Brain Cell Death by Increasing Blood Flow
Laurie Erb, Ph.D.
The Curators of the University of Missouri

Identifying Novel Drug Targets in AD Using Brain Gene Expression
Nilufer Ertekin-Taner, M.D., Ph.D.
Mayo Clinic Jacksonville

Novel Factors that Regulate Alzheimer Disease Pathology
Vivek Gautam, DVM, Ph.D.
Massachusetts General Hospital, Harvard Medical School

Treating Alzheimer’s Disease with Drugs Directed Against the Prion Protein
David A. Harris, M.D., Ph.D.
Boston University School of Medicine

A Novel Therapeutic Approach to the Prevention of Alzheimer's Disease
Joachim Herz, M.D.
The University of Texas Southwestern Medical Center

A New Anti-Inflammatory Therapy for Alzheimer’s Disease
Lee-Way Jin, M.D., Ph.D.
University of California, Davis

Delivery of ACE by Immune Cells to Reduce Aβ Pathology for AD Treatment
Maya Koronyo-Hamaoui, Ph.D.
Cedars-Sinai Medical Center

Understanding the Causal Link Between Brain Blood Flow Reduction and Alzheimer's Disease and Exploring a Novel Nano-Drug
Hongmei Li, Ph.D.
Baylor College of Medicine

New Therapeutic Approach for Alzheimer’s Disease via Apolipoprotein E
Fan Liao, Ph.D.
Washington University

A New Study to Rescue Memory Impairments in Alzheimer’s Disease by Changing a Cellular Signaling Pathway
Tao Ma, M.D., Ph.D.
New York University

Understanding How an Innate Immune Signaling Pathway in Microglia Affects Different Stages of Tau Pathology
Crystal M. Miller, Ph.D.
The Cleveland Clinic Foundation

Studying How HDAC6 influences Toxic Effects of Tau in Alzheimer’s Disease
Leonard Petrucelli, Ph.D.
Mayo Clinic Jacksonville

MicroRNAs and Tau Gene Expression Regulation
Ismael Santa-Maria Perez, Ph.D.
Columbia University Medical Center

Prion Drugs for Alzheimer’s Disease Therapy
Stephen Strittmatter, M.D., Ph.D.
Yale University School of Medicine

Identifying the Disease-Causing Form of the Amyloid Beta-Protein in Human Brain
Dominic Walsh, Bsc. (Hons), P.G.C.E., Ph.D.
Brigham and Women's Hospital

Dissecting the Role of Genetic Factors that Predispose Individuals to Sporadic Alzheimer's Disease
Jessica Young, Ph.D.
University of California, San Diego

A Clinical Study to Treat Alzheimer’s Disease with Magnetic Stimulation of Deep Brain Regions
Abraham Zangen, Ph.D.
Ben-Gurion University of the Negev, Israel

Macular Degeneration

What is the Cause of Macular Degeneration in STGD3 Patients?
Martin-Paul Agbaga, Ph.D.
University of Oklahoma Health Sciences Center

Involvement of MicroRNAs in Retinal Diseases
Tel Aviv University, Israel

Investigation of the Role and Function of Long Non-Coding RNAs, Which are the New Molecular Tools that May Cause Age-Related Macular Degeneration
Venkata Chavali, Ph.D.
University of Pennsylvania School of Medicine

A New Mechanism Linking Lipid and Altered Inflammation in Neovascular AMD
Jing Chen, Ph.D.
Boston Children's Hospital

Investigating if an Uncontrolled Immune Response to Your Own Damaged Cells Causes the Progression of AMD
Sarah L. Doyle, B.A., Ph.D.
Trinity College Dublin, Ireland

New Therapeutic Strategy for Neovascular Age-Related Macular Degeneration
Chenghua Gu, D.V.M., Ph.D.
Harvard Medical School

A New Source of Stem Cells to Treat Age-Related Macular Degeneration
Jonathan Lin, M.D., Ph.D.
University of California, San Diego

Clinical Characterization of Age-Related Macular Degeneration Using Novel Imaging and Functional Techniques
Chi Luu, Ph.D.
Centre for Eye Research Australia, The University of Melbourne, Australia

Drug Discovery for Macular Disease
Dimitrios Morikis, Ph.D.
University of California, Riverside

Development of a New Therapy for Age-Related Macular Degeneration
Marcelo Nociari, PhD.
Joan and Sanford I. Weill Medical College of Cornell University

Role of Cell Metabolism Regulators in Cell Function and Death and Implications for AMD
Magali Saint-Geniez, Ph.D.
The Schepens Eye Research Institute

Tiny RNAs With a Big Role in Age-Related Macular Degeneration
Shusheng Wang, Ph.D.
Tulane University


An Improved Gene Delivery Method to Lower Eye Pressure in Primate Eyes
Curtis Brandt, Ph.D., FARVO
Board of Regents of the University of Wisconsin System, School of Medicine and Public Health

Effects of Prolonged Eye Pressure Elevation on Visual Brain Changes
Kevin Chan, Ph.D.
University of Pittsburgh

New Method of Delivering Therapeutic Proteins to the Eye for the Treatment of Glaucoma
Anna Demetriades, M.D., Ph.D.
Joan and Sanford I. Weill Medical College of Cornell University

Novel Mechanism of Control of Aqueous Fluid Drainage
Michael H. Elliott, Ph.D.
University of Oklahoma Health Sciences Center

Investigating the Biology and Causes of Glaucoma Using Stem Cells
John H. Fingert, M.D., Ph.D.
University of Iowa

A New, Inducible, and Rapid Model of Glaucoma in Mice
Philip J. Gage, Ph.D.
Regents of the University of Michigan

Mechanism of Cell Damage in Glaucoma: Effect of Rapid Depressurization on Cells
Matthew Glucksberg, Ph.D.
Northwestern University

Development of a Patient-Specific Model of Glaucoma
Alex Hewitt, M.B.B.S. (Hons), M. Med. Sci., Ph.D.
Centre for Eye Research Australia, The University of Melbourne, Australia

A Novel Way to Protect Neurons and Axons in the Eyes
Yang Hu, M.D., Ph.D.
Temple University School of Medicine

Stimulation of the Retina to Re-Grow Axons that Allow Eye Cells to Make Connections to the Brain to Allow for Vision Recovery
Richard K. Lee, M.D., Ph.D.
Bascom Palmer Eye Institute (Miami, FL)

A New Imaging Technique to Sensitively Detect Abnormal Changes in the Retinal Nerves
Hyungsik Lim, Ph.D.
Hunter College, CUNY

Cell Replacement Therapy for Glaucoma
Kenneth J. Muller, Ph.D.
University of Miami, Miller School of Medicine

Can We Increase the Number of Drainage Pores in the Eye to Better Treat Glaucoma?
Darryl Overby, Ph.D.
Imperial College London, United Kingdom

A Novel Way to Treat Experimental Glaucoma by Directly Preventing Nerve Axon Damage
John Wood, B.Sc. (Hons.), D.Phil.
South Australian Institute of Ophthalmology, Australia

Protective Role of Nrf2 in Glaucoma
Zhenhua Xu, Ph.D.
Johns Hopkins University

Can Optineurin Protein Aggregate to Form Toxic Amyloid-Like Fibrils or Oligomers?
Beatrice Yue, Ph.D.
University of Illinois Medical Center

Last Review: 01/14/14