Macular Degeneration Research Request for Proposals

Macular Degeneration Research, a BrightFocus Foundation program, provides research funds for U.S. domestic and international researchers pursuing pioneering research leading to greater understanding, prevention, and treatment of age-related macular degeneration.

We are committed to supporting scientists from diverse backgrounds to foster creativity and innovation in addressing complex scientific challenges. We strongly encourage applications from individuals who are from groups underrepresented in the field of age-related macular degeneration research.

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FY25 Dates & Deadlines

Letter of Intent

Application Opens: Thursday, May 29, 2025
Application Deadline: Thursday, July 17, 2025

Full Application (by invitation only)

Deadline: Thursday, December 4, 2025

Due to the large volume of proposals received, we no longer accept proposals by mail or e-mail. You must apply online.

Apply Now
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About the Awards

Macular Degeneration Research offers three types of awards:

A photo of Kelly Mulfaul, a BrightFocus Foundation-funded researcher, working in a lab.

Postdoctoral Fellowship Program

This fellowship program is intended to support young postdoctoral researchers during their final stages of mentored training. The award provides salary support for a young scientist to conduct postdoctoral studies in an established laboratory focused on research contributing to understanding the biological causes and/or new clinical treatment of macular degeneration and should also serve as the basis for the applicant’s independent research career.

  • Proposal Length: Two-page description of the proposed research
  • Award Amount: $100,000 per year (total value $200,000)
  • Duration: 2 years
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New Investigator Grant Program

This research grant program is restricted to new and early investigators who have received their MD, PhD, or equivalent degree and/or completed formal medical training/residency within the past 10 years at the time of application. It is intended to support investigators during their early years as independent investigators involved in studies that have an impact on the causes and/or treatment of macular degeneration.

  • Proposal Length: Two-page description of the proposed research
  • Award Amount: $150,000 per year (total value $450,000)
  • Duration: Up to 3 years
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Innovative Research Grants

This program is intended to provide support for high-risk/high-gain age-related macular degeneration research. We hope to attract established investigators to apply for this support, but the aims of the application must contain outside-the-box ideas that are novel in the field. Applicants who are experts in another field are encouraged to apply their talents to proposing innovative research in the macular degeneration field.

  • Proposal Length: Three-page description of the proposed research
  • Award Amount: Maximum $200,000 per year (total value $600,000)
  • Duration: Up to 3 years

Related News

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New Supplement to Prevent Macular Degeneration Inspires Deeper Search for Cures

A Macular Degeneration Research-funded scientist launched a supplement based on a link he discovered between the eye disease and Parkinson’s disease. Now he’s continuing research in the hopes of finding novel cures.

Daisy Shu, PhD
Macular Degeneration Research grant recipient Daisy Shu, PhD

Transforming Macular Degeneration Care With Long-Acting Treatment

With funding from Macular Degeneration Research, Dr. Daisy Shu is exploring advanced drug delivery systems that release medicine slowly over time. This innovative approach could reduce the number of injections needed for macular degeneration while maintaining vision-saving results.

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How Targeting a Molecular ‘Switch’ Could Inspire New Macular Degeneration Treatments

A researcher funded by BrightFocus’ Macular Degeneration Research is zeroing in on a protein that damages eye cells in the early stages of dry age-related macular degeneration, offering insights that could lead to new treatments.

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How Better Models of Macular Degeneration Could Help Prevent Vision Loss

Most experimental models that researchers use to study macular degeneration fall short. BrightFocus Macular Degeneration Research grant recipient Dr. Brittany Carr aims to change that.

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Is This the Next Best Thing to Regrowing a New Retina?

A BrightFocus Macular Degeneration Research-funded scientist is investigating a new regeneration technique to restore key cells that are wiped out in late-stage age-related macular degeneration.

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Turning Back the Biological Clock on Aged and Injured Eye Cells

A de-aging technique offers hope for halting damage in early macular degeneration.

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New Research Links Blue Light to Macular Degeneration Risk, Antioxidants May Offer Hope

Blue light ​may​ damage the eyes by causing unstable “free radicals” to form, ​which increases the risk of​ age-related macular degeneration. BrightFocus-funded research offers a potential way to protect the eyes from blue light.

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Exosomes: The New Frontier in Early Detection of Macular Degeneration

Motivated by his family’s experience with eye diseases, Dr. Miguel Flores-Bellver is searching for new biomarkers of age-related macular degeneration. 

Dr. Maximilian Pfau (center) and doctoral student Georg Ansari (right) in Dr. Pfau’s laboratory at the Institute of Molecular and Clinical Ophthalmology Basel in Switzerland.

How an Innovative Night Vision Test Could Enable Earlier Detection of Age-Related Macular Degeneration

A BrightFocus Foundation Macular Degeneration Research grant recipient aims to bridge the gap in available testing for AMD and detect the condition as early as possible.

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