Apply for a Research Grant

BrightFocus provides research funds for U.S. domestic as well as international researchers pursuing pioneering research leading to greater understanding, prevention, and treatment of Alzheimer’s disease, macular degeneration, and glaucoma.

Alzheimer’s Disease Research Request for Proposals

Macular Degeneration Research Request for Proposals

National Glaucoma Research Request for Proposals

To start a new application and upload attachments, you must use our ProposalCentral application portal to apply online. Note: Your organization must be registered with ProposalCentral to apply.

Scientist working in lab.
Macular Degeneration Research grant recipient, Yong-Su Kwon, PhD
A female researcher in the lab.

Our Funding Philosophy

It is our firm belief that having the courage to invest in innovative ideas will lead to revolutionary therapies. BrightFocus provides initial funding for highly innovative experimental ideas, including interdisciplinary investigations that may apply to two or three of the BrightFocus disease interests. Most of the awardees use the BrightFocus award funds to demonstrate key findings that lead to later interest and additional funding from industrial or governmental funding agencies.

Grant Application Resources

Frequently Asked Questions

Get answers to applicants’ frequently asked questions, from eligibility to the review process, categorized by each disease program.

Read FAQs

Guidelines

From file type and size to formatting requirements, ensure your application checks the necessary boxes.

Read Guidelines

Terms & Conditions

Your guide to understanding the conditions of funding and the definitions and abbreviations used throughout the grant agreement.

Read Terms & Conditions
A male researcher in the lab.
National Glaucoma Research-funded scientist Ignacio Provencio, PhD.

News

Recent News & Breakthroughs

Browse research news and breakthroughs from BrightFocus-funded scientists.
Stacey Sukoff Rizzo, PhD, far left, shares feedback with students.

4 Takeaways from Alzheimer’s Fast Track 2025

This innovative meeting hosted by BrightFocus Foundation bridges cutting-edge science, mentorship, and community building for early-career researchers.

Understanding Alzheimer's and Exploring New Frontiers in Treatment thumbnail.

Understanding Alzheimer’s & Exploring New Frontiers in Treatment

Watch a conversation inspired by the documentary film Taking Care and the latest research in Alzheimer’s therapies.

Shaping the Future of National Alzheimer’s Research Priorities

BrightFocus Foundation’s VP of Scientific Affairs helped set national research priorities at the federal Alzheimer’s Disease-Related Dementias Summit, influencing how billions in NIH funding will advance dementia research and care.

A researcher looking through a microscope in a lab.

2025 Research Portfolios Spotlight Breakthrough Science

BrightFocus is proudly supporting 186 cutting-edge research grants, fueling the global fight against Alzheimer’s disease, macular degeneration, and glaucoma.

An older man sits on a couch with a glass of water in one hand and a pill pinched between the thumb and forefinger of the other, bringing the pill close to his mouth

New Supplement to Prevent Macular Degeneration Inspires Deeper Search for Cures

A Macular Degeneration Research-funded scientist launched a supplement based on a link he discovered between the eye disease and Parkinson’s disease. Now he’s continuing research in the hopes of finding novel cures.

Dr. Sharyn Rossi and Dr. Keith Hengen.

New Clues in the Fight Against Alzheimer’s: Q&A with Dr. Keith Hengen

During World Alzheimer’s Month, Alzheimer’s Disease Research grantee Dr. Keith Hengen joined BrightFocus’ Dr. Sharyn Rossi on Instagram Live to talk brain health—how the brain functions, why quality sleep matters, and tips to keep your brain healthy.

BrightFocus National Glaucoma Research grant recipient Jennifer Fan Gaskin, MBChB, MD, FRANZCO (far right) with her research team in the lab. Photo courtesy Jennifer Fan Gaskin.

Protecting Vision: A New Approach to Scar-Free Healing From Glaucoma Surgery

BrightFocus National Glaucoma Research-funded scientist Jennifer Fan Gaskin, PhD, is exploring safer, more effective treatments to prevent scarring after glaucoma filtration surgery, also known as trabeculectomy.

2025 cover for annual report.

2025 Annual Report Now Available

BrightFocus Foundation’s 2025 annual report celebrates groundbreaking research and public awareness.

Jason Meyer, PhD working with two team members in his lab.

National Glaucoma Research Grantee Receives $2.2 Million Follow-On Award Aimed at Curing Blindness

Additional funding is propelling BrightFocus-funded scientist Jason Meyer, PhD, toward advances in whole-eye transplantation.

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