People with a medical condition or healthy individuals may consider participating in clinical trials. Each trial has its own protocol, or set of guidelines, and volunteers first must meet certain criteria to qualify for enrollment. Before making a decision and giving their informed consent, each person should seek as much information as possible about the trial, and think seriously about the benefits and risks of volunteering. Benefits to volunteering are actively becoming involved in your own healthcare and the satisfaction of helping others with the medical condition studied in the clinical trial (if you are not affected). However, there may be side effects or the treatments may not be effective, and participation will require a time commitment.
Antidote is a third-party application that allows you to search for clinical trials. It is not affiliated with, or endorsed by, the BrightFocus Foundation or our website. Please see our disclaimer related to third-party sites for more information.
- To learn more about what clinical trials are and how to participate, download our brochure Clinical Trials: Your Questions Answered.
Where Can I Find More Information?
Services to Identify Clinical Trials and Sign up as a Volunteer:
Antidote. Antidote helps you discover new treatment options being developed by medical researchers. They put technology to work so that by answering a few health questions, their smart search engine quickly and easily finds a trial that’s right for you.
Clinicaltrials.gov. An online registry and results database hosted by National Institutes of Health (NIH) that lists all publicly and privately supported clinical studies being conducted with human participants around the world. Follow prompts to look for active clinical trials located near you for a specific medical condition.
eyeGENE®. Aims to advance studies of eye diseases and their genetic causes by giving researchers access to DNA samples, clinical information, and patients looking to participate in research studies and clinical trials.
National Institutes of Health (NIH). Provides information on government-sponsored human trials and recruitment, with locations, purpose, eligibility requirements, and phone contacts.
- National Institute on Aging (NIA)
- National Eye Institute (NEI)
- National Institutes of Health, National Institute of Neurological Disorders and Stroke (NINDS)
They also provide information on health registries:
ResearchMatch. This free and secure registry brings together people who are trying to find research studies, and researchers who are looking for people to participate in their studies.
Additional Resources to Answer Your Questions:
Center for Information and Study on Clinical Research Participation (CISCRP). A nonprofit organization that educates the public about clinical research; what it means to be a clinical research volunteer; and questions you should consider before, during, and after your participation in clinical trials.
U.S. Food and Drug Administration (FDA). The “For Patients” section of the FDA website links to information about clinical trials and the drug and device approval process.
Drug Safety & Reporting:
MedWatch (FDA Safety Information and Adverse Event Reporting Program). A website maintained by the FDA with safety information about drugs commercially available in the United States, including a searchable database. Consumers and healthcare professionals can voluntarily report a serious adverse event, product quality problem, or another type of failure that is suspected to be associated with the use of an FDA-regulated drug, biologic, medical device, dietary supplement, or cosmetic. Suspected counterfeit medical products can also be reported through the same online reporting form.
Information About Online Reporting
Organ and Tissue Donation:
Eye Bank Association of America. A network of eye banks around the country recover corneal tissue from donors and prepare it to surgeons’ specifications for sight-restoring transplant procedures.
NIH NeuroBioBank (NBB). Supported by the National Institute of Mental Health, the National Institute of Neurological Disorders and Stroke, and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the NBB brings together multiple stakeholders to facilitate research advancement through the collection and distribution of human post-mortem brain tissue.
U.S. Department of Health and Human Services. An online resource offering information about “the basics” of organ, eye, and tissue donation, and about who these gifts may help under the U.S.-run Organ Procurement and Transplantation Network.
- Search for Clinical Trials
- The Phases of Clinical Trials
- View or download Clinical Trials: Your Questions Answered (Publication)
- Understanding Clinical Trials (Interviews with Scientists)
BrightFocus is not responsible for the content of these websites and does not endorse any particular programs offered by these organizations.
The information provided here is a public service of the BrightFocus Foundation and should not in any way substitute for personalized advice of a qualified healthcare professional; it is not intended to constitute medical advice. Please consult your physician for personalized medical advice. BrightFocus Foundation does not endorse any medical product or therapy. Also, although we make every effort to keep the information on our website updated, we cannot guarantee that the posted content reflects the most up-to-date understanding.