The Role of Neurofilaments in Alzheimer's Disease

Jean-Pierre Julien, PhD
Montreal General Hospital Research Institute (Montreal, QU Canada)
Year Awarded:
Grant Duration:
April 1, 1996 to March 31, 1998
Alzheimer's Disease
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The Role of Neurofilaments in Alzheimer's Disease



Zhu Q, Lindenbaum M, Levavasseur F, Jacomy H, Julien JP. Disruption of the NF-H gene increases axonal microtubule content and velocity of neurofilament transport: relief of axonopathy resulting from the toxin beta,beta'-iminodipropionitrile. J Cell Biol. 1998 Oct 5;143(1):183-93. PubMed Central PMCID: PMC2132812  

Julien JP, Mushynski WE. Neurofilaments in health and disease. Prog Nucleic Acid Res Mol Biol. 1998;61:1-23. Review.  

Couillard-Despres S, Zhu Q, Wong PC, Price DL, Cleveland DW, Julien JP. Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9626-30. PubMed Central PMCID: PMC21389 PubMed  

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