A Molecular Basis for Selective Neuronal Vulnerability

Dale Bredesen, MD
La Jolla Cancer Research Foundation (La Jolla, CA)
Year Awarded:
1995
Grant Duration:
April 1, 1995 to March 31, 1997
Disease:
Alzheimer's Disease
Award Amount:
$194,680
Grant Reference ID:
A1995064
Award Type:
Standard
Award Region:
US Southwestern

A Molecular Basis for Selective Neuronal Vulnerability

Details


Publications

Keane, R.W., Srinivasan, A., Foster, L.M., Testa, M.P., et al. (1997) Activation of CPP32 during apoptosis of neurons and astrocytes. J. Neurosci. Res. 48(2):168-180.  

[Book Chapter] Murphy, A.N. and Bredesen, D.E. (1997) Mitochondria, reactive oxygen species, and apoptosis. In: Mitochondria and Neurodegenerative Diseases: Mitochondria and Free Radicals in Pathogenesis, M.F. Beal, I. Bodis-Wollner, and N. Howell, eds., Wiley-Liss, New York.

Srinivasan, A., Foster, L.M., Testa, M.P., Ord, T., et al. (1996) Bcl-2 expression in neural cells blocks activation of ICE/CED-3 family proteases during apoptosis. J. Neurosci. 16(18):5654-5660.  

Bredesen, D.E. (1995) Neural apoptosis. Ann. Neurol. 38(6):839-851.  

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