Gene Therapy for Alzheimer's Disease Using HSV1 Vectors
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[Book Chapter] Geller, A.I. (1996) HSV-1 plasmid vectors for gene transfer into neurons. In: Neuronal regeneration, reorganization, and repair. F. Seil, ed., Advances in Neurology, Raven Press, N.Y. 72:143-148.
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[Book Chapter] O'Malley, K.L. and Geller, A.I. (1996) Gene Delivery using HSV-1 plasmid vectors. In: Genetic Manipulation of the Nervous System, D.S. Latchman, ed., pp. 115-126. [Book Chapter] Lim, F., Starr, P., Song, S., Hartley, D. et al. (1995) Methods for using a defective herpes simplex virus (HSV-1) vector system. In: DNA Cloning 4, Mammalian Systems. The Practical Approach Series. D.M. Glover, and B.D. Hames, eds., Oxford Univ. Press, Oxford, pp. 263-283. Geller, A.I., Naegele, J., O'Malley, K., and During, M.J. (1995) Technical comment on 'Long-term behavioral recovery in parkinsonian rats by an HSV vector expressing tyrosine hydroxylase'. Science. 269:856-857.
Geller, A.I., Freese, A., During, M.J., and O'Malley, K.L. (1995) A HSV-1 vector expressing tyrosine hydroxylase causes production and release of L-dopa from cultured rat striatal cells. J. Neurochem. 64:487-496.
Smith, R. L., Geller, A.I., Escudero, K.W., and Wilcox, C.L. (1995) Long-term expression in sensory neurons in tissue culture from herpes simplex virus type 1 (HSV-1) promoters in a HSV-1 -derived vector. J. Virology. 69:4593-4599.
[PMID:nd] Neuwelt, E.A., Pagel, M.A., Geller, A.I., and Muldoon, L.L. (1995) Gene replacement therapy in the central nervous system: Viral vector-mediated therapy of global neurodegenerative disease. Behavioral Brain Sci. 18:1-9.[link not available]
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During, M.J., Naegele, J., O'Malley, K., and Geller, A.I. (1994) Long-term behavioral recovery in Parkinsonian rats by an HSV-1 vector expressing tyrosine hydroxylase. Science. 266(5189):1399-1403.
[PMID:nd] Geller, A.I., During, M.J., and Neve, R.L. (1994) A defective herpes simplex virus vector system for gene transfer into neural cells in the adult brain: Applications to gene therapy and neuronal physiology. Methods Neurosci. 21:443-461.[link not available]
Bahr, B.A., Neve, R.L., Sharp, J., Geller, A.I., and Lynch, G. (1994) Rapid and stable gene expression in hippocampal slice cultures from a defective HSV-1 vector. Brain Res. Mol. Brain Res. 26(1-2):277-285.
First published on: June 10, 2008
Last modified on: September 30, 2010