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BrightFocus Research Grants Funding
Grant Funding for Alzheimer's Research
Grant Funding for Macular Degeneration Research
Grant Funding for Glaucoma Research
 

 

Macular Degeneration Research
Completed Award

Dr. Jimbo Liu

Jinbo Liu, M.D.

Cleveland Clinic Foundation
Cleveland, OH

Title: Identification of autoreactive T cells in AMD Patients
Non-Technical Title: Immune mechanism underlying AMD

Duration: April 1, 2008 - March 31, 2012
Award Type: Standard
Award Amount: $100,000

Summary:

The experiments in this proposal will address the mechanisms underlying immune attack in the retina. This information could lead to treatment approaches not currently available.

Details:

The back of the eye where light is detected is a site where light induced modifications of occular components can occur as individuals age, and these modifications accumulate. The immune system is designed to distinguish anything that differs from normal body components, so these modifications can cause the immune system to attack the back of the eye and compromise vision. The experiments in this proposal will address the mechanisms underlying this immune attack. This information could lead to treatment approaches not currently available.