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Grant Funding for Alzheimer's Research
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Macular Degeneration Research
Completed Award

Dr. Luba Robman

Luba Robman, MBBS, Ph.D.

Centre for Eye Research Australia, The University of Melbourne
Melbourne, Australia

Title: Genetic risks for AMD in Australians of Northern and Southern European origin
Non-Technical Title: Genetic and environmental risks for age-related macular degeneration

Duration: April 1, 2008 - March 31, 2010
Award Type: Standard
Award Amount: $100,000

Summary:

This study will investigate whether the risk of AMD, which is pre-determined by genes, can be modified by changes in diet. The study will genotype AMD cases and controls from a large Australian cohort of participants of Anglo-Celtic and Mediterranean origin to define genetic risk for AMD.

Details:

This study will investigate whether the risk of AMD, which is pre-determined by genes, can be modified by changes in diet. The study will genotype AMD cases and controls from a large Australian cohort of participants of Anglo-Celtic and Mediterranean origin to define genetic risk for AMD. They will identify the AMD genes in elderly from this cohort (about 8,000 people), and correlate genetic status of the participants with their dietary history and condition of the retina. This might be a first step towards personalized medical care, based upon knowledge of susceptibility to a disease using genetic and other risk factor information.

Publications:

Adams MK, Simpson JA, Aung KZ, Makeyeva GA, Giles GG, English DR, Hopper J, Guymer RH, Baird PN, Robman LD. Am J Epidemiol. Abdominal Obesity and Age-related Macular Degeneration. 2011 Mar 21. PubMed Icon Google Scholar Icon

Adams MK, Simpson JA, Richardson AJ, Guymer RH, Williamson E, Cantsilieris S, English DR, Aung KZ, Makeyeva GA, Giles GG, Hopper J, Robman LD, Baird PN. Hum Mol Genet. 2012 Sep 17. PubMed Icon Google Scholar Icon

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