Approximately five years ago I was diagnosed with dry macular degeneration. During a recent eye exam, the doctor informed me that I have developed wet macular degeneration in my left eye. My vision is limited and is very blurry. I am scheduled to receive a series of three injections. How long will the effects of the injections last and does it mean that the right eye will also develop the wet form of this disease? [ 12/17/12 ]
A minority of patients (about 10%) with dry-age related macular degeneration (ARMD) convert to wet ARMD and the most effective treatment for wet ARMD is an injection of a certain type of medication into the eye. In multiple clinical trials, these medications preserved vision in 90% of patients, but improved vision in only 40% of patients. People require different frequencies of treatment, and the most common dosing plan is monthly.
If the left eye has wet ARMD, the right eye is at higher risk of developing wet ARMD. The risk can be as high as 75% in the next five years depending on whether certain features were observed in the right eye during the examinations.
I am 63 years old and have macular degeneration. I recently had cataract surgery, and immediately the vision in my right eye became foggy; instead of seeing straight lines I perceived them as wavy. I had also had cataract surgery on the other eye and probably 90 percent of the time I can hardly open my eyes at when I am outdoors. My eyes are very sensitive. I wish I would have not had the surgery. The doctors never told me anything about this possibility and my life has changed so much. What else could happen to my eyes as a result of the surgeries? [ 12/17/12 ]
Your right eye could be blurry for a variety of reasons including things related to your cataract surgery and/or your age-related macular degeneration (ARMD). You may be light sensitive for a variety of reasons related to one or both processes as well. Without a complete eye exam and possible testing, it would be difficult to differentiate between the multiple things that could be causing your symptoms based on your description alone. You might also consider getting a second opinion from a retina specialist regarding the prognosis of your symptoms and what could be causing those symptoms.
My 91-year-old mother-in-law has been receiving eye injections and she can basically just see light and dark. Should she have to continue to get the injections? Will her vision improve beyond what it is now? [ 12/17/12 ]
Intravitreal eye injections such as Lucentis, Avastin, and Eylea are the most effective treatments for wet age-related macular degeneration (ARMD). In multiple clinical trials, these injections preserved vision in 90 percent of patients, but improved vision in only 40 percent of patients. Your mother-in-law may be in the 90 percent of patients that that eye injections preserve vision in, but not in the 40 percent of patients that notice significant visual gain after injection. Your mother-in-law's vision may improve with continued injection, and the vision could decline if injections are stopped. Predicting these outcomes is very challenging and depends on a variety of factors. Please discuss the potential results of stopping or having less frequent injections with your retina specialist.
I have wet age-related macular degeneration in one eye. How likely is it that the other eye be affected? [ 12/17/12 ]
If the one eye has wet age-related macular degeneration (ARMD) the other eye is at higher risk of developing wet ARMD. The risk can be as low as 10 percent and as high as 75 percent in the next five years depending on whether certain features were observed in the eye with dry ARMD. Speak to a retina specialist about your eye exam findings, what specific risk you have for developing wet ARMD, and if you would benefit from taking a formula of eye vitamins for patients with high risk dry ARMD. This vitamin formula has been shown to help prevent conversion of dry ARMD to wet ARMD in a certain subset of patients.
I have twice undergone chemotherapy for hepatitis C. The first treatment started to shut down my bone marrow and they discontinued it, and during the second treatment, a substance was added to the alpha-interferon, which I believe was called Rebetron or Reprotron. Soon after this second treatment I was soon diagnosed with diabetes and macular degeneration. There is no diabetes for any male on my father’s side of my family, and no one has had macular degeneration. I believe both treatments caused depression and vision problems. Is there evidence that these treatments can cause either diabetes or macular degeneration? Thank you. [ 12/17/12 ]
Rebotron is a combination treatment of ribavarin and interferon for the hepatitis C virus. No definitive link has been established concerning the use of these medications and developing or worsening of age-related macular degeneration (ARMD). Interferon can cause a variety of other changes in the eye however, so you should have a full examination by an ophthalmologist. Also, interferon has previously been associated with development of diabetes, so please discuss this with your medical doctor prescribing the Rebotron.
I am 70 years old and have wet age-related macular degeneration. I completely lost the central vision in my right eye after 49 Lucentis injections. For approximately nine months, the macula stayed dry, but now it is back to the usual state. What are the chances of getting some good benefits by starting the injections again? [ 12/17/12 ]
Lucentis is a common treatment for wet age-related macular degeneration (ARMD), however this eye injection does not cure the disease; the injection only controls the disease. It is not uncommon to eventually require treatment again after stopping Lucentis as the wet ARMD may recur. Restarting Lucentis injections would be a good option to preserve and possibly improve the vision from where it is now. Your specific prognosis depends on what kind of damage the wet ARMD has done to your eye and is best directed to your retina specialist after he or she has performed a complete examination and eye studies. In some patients, vision is lost after stopping Lucentis therapy that is not regained when restarting therapy.
If someone receives two Eylea injections, can they terminate the rest of the shots without adverse effects? [ 12/17/12 ]
Eylea is a common treatment for wet age-related macular degeneration (ARMD), however this eye injection does not cure the disease; the injection only controls the disease. Some patients require lifelong treatment. Stopping ARMD treatment with Eylea before the wet ARMD is completely under control may result in permanent vision loss, or loss of the ability to improve vision with subsequent injections. Please talk with your retina specialist about your specific reasons for wanting to stop the Eylea injections as this action may have substantial impact your vision.
My 32-year-old son has suffered from wet macular degeneration since the age of 15, when it was discovered in his right eye; there was nothing anyone could do about it. At the age of 20, the left eye started deteriorating and there was evidence of choroidal neovascularization (CNV). He had been treated with about eleven photodynamic treatments and three Avastin injections in his left eye. The scar keeps growing and his vision is becoming worse. We live in Israel, and the eye test results are around 6/30 in both eyes. (I am not familiar with your measuring system) Is there any way to help him and stop this deterioration? [ 12/17/12 ]
Wet age-related macular degeneration typically does not manifest itself in patients younger than 55 years of age. Your son has likely developed choroidal neovascularization (CNV) secondary to a different type of macular degeneration. Both Avastin and photodynamic therapy are common treatments for CNV. Without knowing the specific subtype of macular degeneration or seeing the results of the clinical exam, I cannot give a specific prognosis or treatment recommendation to preserve vision. Your son may benefit from evaluation by a low vision specialist. This specialist can help your son maximize his remaining vision with various assistive devices and training.