Is there research evidence showing a link between new macular bleeding and warfarin use with INR kept between 2 and 3? I am on warfarin and acetylsalicylic acid as a result of AMIx2 and chronic atrial fibrillation. I also have had Avastin shots for four years with recent renewed bleeding. Thank you for your thoughts. [ 03/08/13 ]
There are reports linking warfarin use with development of wet age-related macular degeneration/macular bleeding. According to a 2003 research report in Heart, Volume 89, issue 9, p.985, it is recommended that the international normalized ratio (INR) be kept on the lower end of the recommended range in patients with a history of or recent diagnosis of wet macular degeneration/macular bleeding. Your eye doctor can provide you with more detailed information about your specific situation.
I have two daughters with dry macular degeneration, and I am concerned about my two sons also developing this eye disease. Is macular degeneration more prominent in females or males? [ 03/08/13 ]
Genetics contribute to age-related macular degeneration (ARMD), so if your daughters have dry ARMD, your sons are also at higher risk for developing the disease. ARMD is also age related, and this disease more commonly manifests itself with increasing age. No clear link has been established between ARMD being more common in either men or women. Though most scientific studies have not found that ARMD is more common in either men or women, a handful of other studies have demonstrated a slight increase in prevalence of ARMD in women.
I have the dry form of age-related macular degeneration and had some questions about an online article that indicated aspirin was not recommended for people that have this eye disease. I am being prescribed one regular tablet daily as I have a tendency to clot due to Factor V. Also, I had an accident that required a hemi-hip replacement, which caused the development of a clot. I was put on Coumadin for six months and then aspirin. Do these medications have an impact on macular degeneration? [ 03/08/13 ]
The exactly link between aspirin and worsening of age-related macular degeneration (ARMD) is not known. Three well designed studies have reported a possible association between aspirin usage and worsening of ARMD. Likewise, three other independent well designed studies did not find this relationship. Thus no clear relationship has been defined between aspirin and ARMD. You should discuss your concerns with the physician prescribing the medications and continue taking the aspirin until you talk with him/her. Importantly, do not stop the aspirin unless it is recommended by the physician who regularly prescribes your blood thinners.
My niece, who is currently eight and one-half years old, has recently been diagnosed with heredomacular degeneration in India. The results show that region to the right of the central retina is 40 percent blurry and the left side is just 15 percent. She is having a hard time taking notes in school or reading. She has to hold a book very closely to read. The doctor, a retina specialist, says that there is no cure for this disease; however, I believe there is some treatment or permanent solution. She has her entire life to live. Please guide us and let me know if this is curable and also suggest how I can find doctors in Mumbai or any place in India who have more knowledge. Thanks! [ 03/08/13 ]
Many types of hereditary macular degeneration can affect young children, and the prognosis varies considerably depending on the exact type of macular degeneration. Your niece may benefit from evaluation by an academic retina center, and also evaluation by a low vision specialist. An academic center may be able to help establish a firm diagnosis for your niece. Strong academic centers in India include L. V. Prasad Eye Institute in Hyderabad and Aravaind Eye Institute in Madurai. Your retina specialist may be able to send your nieces’ retina photos for an opinion from specialists at either of these or other centers. Moorfields Eye Hospital in London has a particularly strong inherited retinal disease department as well. A low vision specialist can help your niece maximize her existing vision. With training and assistive devices from a low vision specialist, your niece may have an easier time reading, taking notes, and completing other tasks of daily living. Your current retina specialist can likely give you a referral to a local low vision specialist. Most large eye centers have therapists with this expertise on staff.
I have dry macular degeneration. Does taking aspirin affect the onset of wet macular degeneration? [ 12/20/12 ]
Some studies have reported an increased association between aspirin consumption and a slight increase in rates of various types of late-stage age-related macular degeneration (AMD. This theory is still undergoing study, as the association shown does not prove cause and effect. In other words, these studies do not explain how aspirin might be causing increased progression of AMD, only that it people at higher risk for AMD are often taking aspirin. Aspirin is often prescribed against pain and heart disease, and is used regularly by about nearly 1 in 5 people in the US.
It is always prudent to consult your physician(s) before taking supplements and either over-the-counter or prescription medications. Your physician will be able to help balance potential risks against the other potential health benefits of any activity, including taking aspirin.
My husband has been taking Lucentis injections for a year and he's not getting any better or worse. His doctor wants to try another treatment. Are there any other treatment alternatives? [ 12/17/12 ]
If your husband has wet age-related macular degeneration (ARMD), Lucentis is a very common treatment. In clinical trials, Lucentis preserved vision in 90% of patients, but improved vision in only 40% of patients with wet ARMD. Your husband many not belong to the 40% of patients that notices significant visual improvement after Lucentis treatment. Other commonly used treatments for ARMD include Eylea and Avastin, which have comparable treatment success rates to Lucentis. Some patients may react better to one eye injection compared to another. Ask your husband's retina specialist if a trial of one of these other wet ARMD injections would be appropriate.
I am 63 years old and have macular degeneration. I recently had cataract surgery, and immediately the vision in my right eye became foggy; instead of seeing straight lines I perceived them as wavy. I had also had cataract surgery on the other eye and probably 90 percent of the time I can hardly open my eyes at when I am outdoors. My eyes are very sensitive. I wish I would have not had the surgery. The doctors never told me anything about this possibility and my life has changed so much. What else could happen to my eyes as a result of the surgeries? [ 12/17/12 ]
Your right eye could be blurry for a variety of reasons including things related to your cataract surgery and/or your age-related macular degeneration (ARMD). You may be light sensitive for a variety of reasons related to one or both processes as well. Without a complete eye exam and possible testing, it would be difficult to differentiate between the multiple things that could be causing your symptoms based on your description alone. You might also consider getting a second opinion from a retina specialist regarding the prognosis of your symptoms and what could be causing those symptoms.
Approximately five years ago I was diagnosed with dry macular degeneration. During a recent eye exam, the doctor informed me that I have developed wet macular degeneration in my left eye. My vision is limited and is very blurry. I am scheduled to receive a series of three injections. How long will the effects of the injections last and does it mean that the right eye will also develop the wet form of this disease? [ 12/17/12 ]
A minority of patients (about 10%) with dry-age related macular degeneration (ARMD) convert to wet ARMD and the most effective treatment for wet ARMD is an injection of a certain type of medication into the eye. In multiple clinical trials, these medications preserved vision in 90% of patients, but improved vision in only 40% of patients. People require different frequencies of treatment, and the most common dosing plan is monthly.
If the left eye has wet ARMD, the right eye is at higher risk of developing wet ARMD. The risk can be as high as 75% in the next five years depending on whether certain features were observed in the right eye during the examinations.