Clinical Trial Information for Glaucoma
Date: October 6, 2011
Topic: Clinical Trial Information for Glaucoma
Katherine Jimenez: Hi, I’m Katherine Jimenez,
Sarah: And I’m Sarah DiSandro. And we’re with National Glaucoma Research, a program of the BrightFocus Foundation, a nonprofit organization leading the fight to save sight and mind.
Sarah DiSandro: Today, we are talking about clinical trial information for glaucoma.
Katherine Jimenez: I’m glad we’re covering this topic today. It’s important to understand the process of how an idea in the mind of a scientist actually becomes a product on a patient’s bedside table.
Sarah DiSandro: It’s true. It can take many years for a potential treatment for glaucoma to work its way from the laboratory to rigorous testing and, finally, approval by the U.S. Food and Drug Administration (FDA).
The process begins in the lab with basic investigations using cells and specially bred animal models. Next, translational research moves the therapy to the human setting. And, finally, the drug is tested on humans in clinical trials divided into three phases: Phase I, Phase II, and Phase III. These trials are used to determine the safety and effectiveness of the drug on progressively larger numbers of people. Normally, if the results are positive in those first two phases, the therapy will proceed to Phase III. The data gathering, analysis, and reporting that are necessary to complete these trials can take several years.
Both those with glaucoma and healthy people may consider participating in clinical trials. Each trial has its own protocol or set of guidelines, and volunteers must meet certain criteria to qualify for inclusion. Before making a decision, get as much information as possible about the trials and think seriously about the benefits and risks of volunteering. Those who participate may have access to medical care, and they are helping others with glaucoma by taking these experimental treatments. However, there may be side effects or the treatments may not be effective, and participation will require a time commitment.
Katherine Jimenez: If you would like information on clinical trials taking place now, you can visit the National Institutes of Health, National Eye Institute.They provide information on government-sponsored human trials and recruitment, with locations, purpose, eligibility requirements, and phone contacts. Visit clinicaltrials.gov or nei.nih.gov/neitrials. Their phone number is (301)-496-5248.
You can also visit the CenterWatch Clinical Trials Listing Service.They provide information about clinical research, including listings of active industry and government-sponsored clinical trials, research on new drug therapies, and drugs recently approved by the FDA. Visit centerwatch.com or call 1-866-219-3440.
Sarah DiSandro: Well, that covers our podcast for today. Thanks for listening.
Katherine Jimenez: Thanks everyone for listening. Stay tuned for future podcasts on glaucoma. For more information about glaucoma or to get involved in advancing research to end this degenerative eye disease, visit brightfocus.org, or call 1-855-345-6NGR. Again, that’s 1-855-345-6647. Thank you.
Last Review: 08/30/13