Findings: This 10-year, follow-up research study, involving nearly 4,000 people from Rotterdam, Netherlands, concluded that women who were obese—with a high body mass index (BMI)— have a slightly lower risk of developing open-angle glaucoma (OAG) than women who weigh less. In particular, the researchers concluded that “a 7% reduction in risk of developing OAG for each unit increase in BMI in women.” The reasons for this are not known, and the researchers suggested there could be confounding factors that account for this decrease. Nevertheless, they announced that their data are statistically significant and that these results confirm the findings of an earlier study completed by a separate team of researchers.
Relevance: The difference between men and women for the risk of developing glaucoma could be due to hormonal or other biological reasons.
- Reference: Wishal D. Ramdas; Roger C. W. Wolfs; Albert Hofman; Paulus T. V. M. de Jong; Johannes R. Vingerling; Nomdo M. Jansonius, Lifestyle and Risk of Developing Open-Angle Glaucoma: The Rotterdam Study. Arch Ophthalmol, Feb 2011; doi:10.1001/archophthalmol.2010.373
- For the full press release from Jama and Archives, please visit: http://pubs.ama-assn.org/homepage/media/2011a/0214.dtl#7