Pushing the Limits of Scientific Knowledge
Since the National Glaucoma Research (NGR) program began in 1978, BrightFocus has awarded more than $22.6 million to support research projects on the causes and potential prevention and treatment of this disease. NGR is currently supporting 31 biomedical research projects, after recently awarding 16 new grants in 2013.
Exciting New Research Projects
- A new mechanism controlling the drainage of eye fluid
- A new way to protect nerve cells in the eyes
- Stimulation of the retina to re-grow axons that allow eye cells to make connections to the brain, allowing for the recovery of vision
- An improved gene delivery method to lower eye pressure
- Cell replacement therapy for glaucoma
Research results from BrightFocus-supported studies that could lead to breakthroughs in stopping glaucoma include:
- The inhibition of the protein, Grp94, could lead to new treatments for some forms of hereditary glaucoma.
- Targeted x-ray treatment provides protection from glaucoma in mice.
- A new clue to the origins of glaucoma comes from a protein that blocks eye drainage.
- Higher oxygen levels in the eyes of African Americans may help explain glaucoma risk.
- Two genetic mutations are linked to normal-pressure glaucoma.
- Small episodes of stress to the eyes may actually protect against damage from glaucoma.
- Zebrafish may hold the key to repairing serious eye conditions.